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zinc oxide nanoparticles toxicity

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2018 Dec;125:252-261. doi: 10.1016/j.micpath.2018.09.030. CAS Article PubMed Google Scholar 2016 Dec;35(12):1286-1304. doi: 10.1177/0960327116629530. Introduction: Epub 2015 May 18. Zinc oxide nanocomposites show also selective toxicity toward normal and cancerous cells, which is explained by reactive oxygen formation (ROS). Int J Nanomedicine. 2018 Dec 20;14:87-100. doi: 10.2147/IJN.S186888. Król A, Pomastowski P, Rafińska K, Railean-Plugaru V, Buszewski B. Adv Colloid Interface Sci. 2020 Sep 30;8:778. doi: 10.3389/fchem.2020.00778. HHS National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. 45. Many microorganisms exist in the range from hundreds of nanometers to tens of micrometers. Antibacterial activity of zinc oxide nanoparticles (ZnO-NPs) has received significant interest worldwide particularly by the implementation of nanotechnology to synthesize particles in the nanometer region.  |  In-Vitro cytotoxicity, antibacterial, and UV protection properties of the biosynthesized Zinc oxide nanoparticles for medical textile applications. Sci Rep. 2020 Nov 17;10(1):19996. doi: 10.1038/s41598-020-76402-w. Jain D, Shivani, Bhojiya AA, Singh H, Daima HK, Singh M, Mohanty SR, Stephen BJ, Singh A.  |  Material and methods: Recent Advances in Nanotechnology-Aided Materials in Combating Microbial Resistance and Functioning as Antibiotics Substitutes. Nano-Micro Letters, 7, 219-242 (2015). They can also be utilized as a self-cleaning coating material on glass and ceramic surfaces. Mohd Yusof H, Abdul Rahman N, Mohamad R, Zaidan UH, Samsudin AA. The nanoparticles (NPs) have been increasingly manufactured in industry because of the well-known characteristics such as high reactivity, electromagnetic properties and high antibacterial property [].Zinc oxide nanoparticle (nZnO), one of the most popular manufactured metal oxide nanomaterials, has unique properties (i.e., surface area and reactive sites) due to the extremely small … Several studies of ZnO NPs cytotoxicity have been conducted and they have shown that zinc oxide nanoparticles can affect many different animal cells , , , , , , , , , . Whether zinc nanoparticles (NPs) are phytotoxic or beneficial to plants remains controversial because of limited research. USA.gov. 43). Zinc is a Block D, Period 4 element, while Oxygen is a Block P, Period 2 element. Zinc oxide NPs can be synthesized by a number of physical, chemical and biological methods. In the past two decades, ZnO NPs have become one of the most popular metal oxide nanoparticles in biological applications due to their excellent biocompatibility, economic, and low toxicity. Furthermore, zinc oxide nanoparticles induced cytotoxicity in human lung epithelial cells via inducing oxidative stress in a concentration-dependent manner, resulting in DNA damage and apoptosis [36 Sahu D, Kannan GM, Vijayaraghavan R, Anand T, Khanum F. Nanosized zinc oxide induces toxicity in human lung cells. Comparison of the mechanism of toxicity of zinc oxide and cerium oxide nanoparticles based on dissolution and oxidative stress properties. ISRN Toxicol 2013; 2013: 316075. Bobrowska-Korczak B, Gątarek P, Skrajnowska D, Bielecki W, Wyrebiak R, Kovalczuk T, Wrzesień R, Kałużna-Czaplińska J. Nutrients. A severe to slight damage was observed in liver tissue in all groups and tissue destruction was seen in kidney only in acute dose treated groups but no specific pathological effect in testis was observed (Fig. Epub 2015 Aug 24. Corrigendum to "Zinc oxide nanoparticles: synthesis, antiseptic activity and toxicity mechanism" Adv Colloid Interface Sci 249 (2017) 37-52. Zitao Zhou, Jino Son, Bryan Harper, Zheng Zhou, Stacey Harper, Influence of surface chemical properties on the toxicity of engineered zinc oxide nanoparticles to embryonic zebrafish, Beilstein Journal of Nanotechnology, 10.3762/bjnano.6.160, 6, (1568-1579), (2015). 2016 Jan;100(2):571-81. doi: 10.1007/s00253-015-7108-x. 2012 May 2;12:60. doi: 10.1186/1472-6882-12-60. 2018 Apr;254:100. doi: 10.1016/j.cis.2018.04.006. Role of quercetin and arginine in ameliorating nano zinc oxide-induced nephrotoxicity in rats. eCollection 2020. They exhibit antibacterial, anti-corrosive, antifungal and UV filtering properties.  |  In the present study, it was found that ZnO‐engineered nanoparticle (ZnO‐EN) toxicity to the marine diatom Thalassiosira pseudonana could be solely explained by … However, under seasonal variation and global climate change, marine organisms are exposed to a changing environment with different regimes of temper Environmental Science: Nano Recent HOT Articles The obtained nanoparticles can be characterized with a broad range of analytical methods including dynamic light scattering (DLS), electron microscopy (TEM, SEM), UV-VIS spectroscopy, X-ray diffraction (XRD) or inductively coupled plasma with mass spectrometry (ICP-MS). ZnO-NPs exhibit attractive antibacterial properties due to increased specific surface area … J Nanosci Nanotechnol 2010, 10: 8617–8624. Zinc oxide nanoparticles (ZnO-NPs) have been reported as an antimicrobial agent against both pathogenic and spoilage microorganisms ... L. C., Bakhori, S. K. M., Mohamad, D., Review on zinc oxide nanoparticles: Antibacterial activity and toxicity mechanism. Environmental Science and Pollution Research 2019 , 26 (3) , … The purpose of this study was to characterize the zinc oxide nanoparticles (ZnO-NPs) and their bulk counterpart in suspensions and to access the impact of their acute oral toxicity at doses of 300 and 2000 mg/kg in healthy female Wistar rats. Literatures available on ZnO nanoparticles toxicity suggest that dissolution, organism dependent cellular uptake, generation of reactive oxygen species (ROS), and induced inflammatory responses seem to be common factors which govern the toxicity of ZnO nanoparticles. Yet despite the potentially interesting antitumor activity of ZnO nanoparticles, it has been proven that they can be also cytotoxic and genotoxic for multiple types of human cells (i.e. 2020 Oct 2;15:7329-7358. doi: 10.2147/IJN.S265934. Appl Microbiol Biotechnol. The increasing focus on nano zinc oxide resulted in the invention and development of methods of nanoparticles synthesis. COVID-19 is an emerging, rapidly evolving situation. Nanoscale. National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. Zinc oxide (ZnO), as a material with attractive properties, has attracted great interest worldwide, particularly owing to the implementation of the synthesis of nano-sized particles. Recently, various approaches including physical, chemical and biological ("green chemistry") have been used to prepare ZnO nanocomposites with different morphologies. Zinc oxide nanocomposites show also selective toxicity toward normal and cancerous cells, which is explained by reactive oxygen formation (ROS). Effects of zinc oxide nanoparticles and/or zinc chloride on biochemical parameters and mineral levels in rat liver and kidney. This helps to place the in vivo behavior of zinc oxide nanoparticles in the proper context. The impact of morphology and size of zinc oxide nanoparticles on its toxicity to the freshwater microalga, Raphidocelis subcapitata. This paper reviews the methods of synthesizing zinc oxide nanocomposites as well as their characteristics, antimicrobial activity and cytotoxicity against normal and tumor cells. Get the latest public health information from CDC: https://www.coronavirus.gov, Get the latest research information from NIH: https://www.nih.gov/coronavirus, Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. This site needs JavaScript to work properly. While their general toxicity and associated oxidative stress have been extensively studied, the toxicological pathways that they induce in developmental stages are still largely unknown. Effect of Zinc Supplementation on the Serum Metabolites Profile at the Early Stage of Breast Cancer in Rats.  |  Results: PMID: 30489211 [Indexed for MEDLINE] Publication Types: Review; MeSH terms. This study investigates the toxic effects of ZnO-NPs in human lung cells. The aim of this work was to investigate the sensitivity and adaptability of five bacterial species isolated from sewage towards Ag and ZnO NPs. Zinc oxide (ZnO) has long been recognized as an effective sunscreen agent. This article provides further detail on the properties and applications of zinc oxide nanoparticles (ZnO). High luminescent efficiency, a wide band gap (3.36eV), and a large exciton binding energy (60meV) has triggered intense research on the production of nanoparticles using different synthesis methods and on their future applications. However, their potential toxicological impact on environmental microorganisms is largely unexplored. Copyright © 2017 Elsevier B.V. All rights reserved.  |  Zinc oxide nanoparticles (ZnO NPs) are being utilized in an increasing number of fields and commercial applications. neuronal or epithelial cells). NIH Int J Nanomedicine. It has been shown that maximum exposure concentration of zinc oxide (125 mg/l) suspension released 6.8 mg/l of Zn 2+ ions. NLM Please enable it to take advantage of the complete set of features! We evaluate the potential of zinc oxide nanoparticles as innovative anti-tumor agents by summarizing important results of current studies in this field and discuss the proposed mechanisms that give zinc oxide nanoparticles a selective toxicity for tumor cells. Front Chem. 30 nm) showed that small particles in aquatic systems and their bioavailability does not have to be significantly greater than that of larger particles. Keywords: Biosynthesis of zinc oxide nanoparticles using. ZnO nanomaterials can be used in industry as nano-optical and nano-electrical devices, in food packaging and in medicine as antimicrobial and antitumor agents. acute and chronic doses; blood parameters; liver tissue. 2020 Nov 11;12(11):3457. doi: 10.3390/nu12113457.  |  In the present study 36 male Wistar rats with approximate age of two months and weighing 300±30 g were selected. Using ICP-MS and fluorescent-labeled ZnO, it is found that ZnO dissolution could happen in culture medium and endosomes. Toxicity of zinc oxide nanoparticles on adult male Wistar rats. A severe to slight damage was observed in liver tissue … Keywords: While their general toxicity and associated oxidative stress have been extensively studied, the toxicological pathways that they induce in developmental stages are still largely unknown. Accute Toxicity Satureja ZnO Nanoparticles Bioassay Test LC 50 96h Abstract Nanoparticles are commonly synthesized chemically and because of their risk for living was carried out to evaluate the acute toxicity of zinc oxide nanoparticles synthesized from Satureja hortensis on rainbow trout (Oncorhynchus mykiss) by static bioassay test. This site needs JavaScript to work properly. Happy Agarwal, Soumya Menon, Venkat Kumar S, Rajeshkumar S. Chem Biol Interact. COVID-19 is an emerging, rapidly evolving situation. Zinc oxide (ZnO) has been characterized as a “Generally Recognized as Safe” (GRAS) compound by the US FDA and exhibits minimal toxicity to humans. After the determined time for every group (21 days for chronic groups and 7 days for acute groups), blood samples were provided from rat hearts and also liver, kidney and testicular tissue were removed for histological studies. Nowadays, a lot of studies were carried out about side effects of nanoparticles especially nano-zinc oxide, but unfortunately, most of these studies have been conducted with high doses. DOI: 10.1007/s40820-015-0040-x Corpus ID: 3669662. Review on Zinc Oxide Nanoparticles: Antibacterial Activity and Toxicity Mechanism @article{Sirelkhatim2015ReviewOZ, title={Review on Zinc Oxide Nanoparticles: Antibacterial Activity and Toxicity Mechanism}, author={Amna Sirelkhatim and S. Mahmud and A. Seeni and Noor Haida Mohamad Kaus and Ling Chuo Ann and S. K. M. Bakhori and … Animals HHS 2018 Apr 25;286:60-70. doi: 10.1016/j.cbi.2018.03.008. Clipboard, Search History, and several other advanced features are temporarily unavailable. Clipboard, Search History, and several other advanced features are temporarily unavailable. Wang LJ, Wang L, Ding WJ, Zhang F: Acute toxicity of ferric oxide and zinc oxide nanoparticles in rats. In this study, we investigated the effect of various concentrations of zinc oxide (ZnO) NPs (0, 1, 5, 20, 100, and 1000 mg kg −1 of soil) on lettuce (Lactuca sativa L.) and carrot (Daucus carota subsp. Srivastav AK, Kumar M, Ansari NG, Jain AK, Shankar J, Arjaria N, Jagdale P, Singh D. Hum Exp Toxicol. The ZnO nanomaterials release into the aquatic ecosystems through domestic and industrial wastewaters has the potential to induce pernicious effects on fish and other organisms. 2014 Nov;33(11):1150-7. doi: 10.1177/0960327113510327. A comprehensive toxicity study of zinc oxide nanoparticles versus their bulk in Wistar rats: Toxicity study of zinc oxide nanoparticles. Please enable it to take advantage of the complete set of features! Epub 2018 Mar 15. ZnO induced toxicity in both cells, leading to the generation of reactive oxygen species (ROS), oxidant injury, excitation of inflammation, and cell death. Microb Pathog. USA.gov. Mechanistic study on antibacterial action of zinc oxide nanoparticles synthesized using green route. Biosynthesis of zinc oxide nanoparticles by cell-biomass and supernatant of Lactobacillus plantarum TA4 and its antibacterial and biocompatibility properties. Amara S, Slama IB, Mrad I, Rihane N, Khemissi W, El Mir L, Rhouma KB, Abdelmelek H, Sakly M. Hum Exp Toxicol. Xia T, Kovochich M, Liong M, et al. After standard phases of preparation, injections were done intraperitoneally in chronic groups with zinc oxide nanoparticles (20 and 40 mg/kg) every other day and for acute groups with 200 and 400 mg/kg in a single dose. Toxicity is a combined effect of zinc oxide nanoparticles and Zn 2+ ions released in the aqueous medium. 2016 Aug;161:441-9. doi: 10.1016/j.jphotobiol.2016.06.007. Fouda A, El-Din Hassan S, Salem SS, Shaheen TI. Hidden toxicity of zinc oxide nanoparticles. Epub 2014 Feb 5. Review on Zinc Oxide Nanoparticles: Antibacterial Activity and Toxicity Mechanism View 0 peer reviews of Review on Zinc Oxide Nanoparticles: Antibacterial Activity and Toxicity Mechanism on Publons COVID-19 : add an open review or score for a COVID-19 paper now to ensure the latest research gets the extra scrutiny it needs. Zinc oxide nanoparticles (ZnO NPs) are being utilized in an increasing number of fields and commercial applications. 10.1166/jnn.2010.2483. Yet despite the potentially interesting antitumor activity of ZnO nanoparticles, it has been proven that they can be also cytotoxic and genotoxic for multiple types of human cells (i.e. Zinc oxide nanoparticles (ZnO NPs) are used in an increasing number of industrial products such as rubber, paint, coating, and cosmetics. The purpose of this study was to characterize the zinc oxide nanoparticles (ZnO-NPs) and their bulk counterpart in suspensions and to access the impact of their acute oral toxicity at doses of 300 and 2000 mg/kg in healthy female Wistar rats. Effect of annealing temperature on antimicrobial and structural properties of bio-synthesized zinc oxide nanoparticles using flower extract of Anchusa italica. Azizi S, Mohamad R, Bahadoran A, Bayat S, Rahim RA, Ariff A, Saad WZ. NLM Microbial Fabrication of Zinc Oxide Nanoparticles and Evaluation of Their Antimicrobial and Photocatalytic Properties. It is now widely recognized that dissolution plays an important role in metallic nanoparticle toxicity, but to what extent remains unclear. Toxicity of zinc oxide nanoparticles through oral route Surekha Pasupuleti, Srinivas Alapati, Selvam Ganapathy, Goparaju Anumolu, Neelakanta Reddy Pully, and Balakrishna Murthy Prakhya Toxicology and Industrial Health 2011 28 : 8 , 675-686 neuronal or epithelial cells). Franklinet al. Abbasalipourkabir R, Moradi H, Zarei S, Asadi S, Salehzadeh A, Ghafourikhosroshahi A, Mortazavi M, Ziamajidi N. Food Chem Toxicol. sativus) plants. 2015 Oct;84:154-60. doi: 10.1016/j.fct.2015.08.019. ; nano-zinc oxide; oxidative stress. RESEARCH ARTICLE Zinc oxide and silver nanoparticles toxicity in the baker’s yeast, Saccharomyces cerevisiae Imelda Galva´ n Ma´ rquez1, Mergan Ghiyasvand1, Andrey Massarsky2¤, Mohan Babu3, Bahram Samanfar1,4, Katayoun Omidi1, Thomas W. Moon2, Myron L. Smith1*, Ashkan Golshani1* 1 Department of Biology and Ottawa Institute of Systems Biology, Carleton University, … Faddah LM, Abdel Baky NA, Al-Rasheed NM, Al-Rasheed NM, Fatani AJ, Atteya M. BMC Complement Altern Med. With the wide application of ZnO-NPs, concern has been raised about its unintentional health and environmental impacts. Would you like email updates of new search results? Zinc oxide nanoparticles (ZnO-NPs) are among nanoscale materials displaying exponentially growing production due to their applications in the field of cosmetology, medicine, as antibacterial agent and catalyst. It indicates an important role of Zn 2 + ions in the cytotoxicity of zinc oxide nanoparticles. Biotechnological aspects of ZnO nanoparticles: overview on synthesis and its applications. Wang Y, Yuan L, Yao C, et al. ZnO nanopowders are available as powders and dispersions. eCollection 2019. This kind of nanomaterial shows serious adverse effects on human respiratory system as it can pass through alveolar epithelial cells into lung … Epub 2015 Nov 6. A combined toxicity study of zinc oxide nanoparticles and vitamin C in food additives. Would you like email updates of new search results? Toxicity of zinc oxide nanoparticles is concentration and solubility dependent. With these it is possible to obtain information concerning the size, shape and optical properties of nanoparticles. Epub 2016 Jun 7. eCollection 2020. Zinc oxide nanoparticles are nanoparticles of zinc oxide (ZnO) that have diameters less than 100 nanometers. Uzar NK, Abudayyak M, Akcay N, Algun G, Özhan G. Toxicol Mech Methods. Epub 2018 Sep 18. 2014;6(24):15333–15342. compared the toxicity of various metal oxide nanoparticles and zinc chloride to a Freshwater Microalga. NIH Silver and zinc oxide nanoparticles (Ag and ZnO NPs) are widely used as antimicrobial agents. Zinc oxide nanoparticles induced cyto- and genotoxicity in kidney epithelial cells. Zinc oxide nanoparticles (ZnO-NPs) are increasingly used in sunscreens, biosensors, food additives, pigments, rubber manufacture, and electronic materials. 2015;25(4):334-9. doi: 10.3109/15376516.2015.1045654. Toxic effect of nano-zinc oxide There were significant decreases in lymphocytes and platelet counts and significant increases in white blood cells count, hemoglobin and hematocrit in acute dose compared to control group and no difference in red blood cells count in all groups. Khan MF, Husain FM, Zia Q, Ahmad E, Jamal A, Alaidarous M, Banawas S, Alam MM, Alshehri BA, Jameel M, Alam P, Ahamed MI, Ansari AH, Ahmad I. ACS Omega. Epub 2016 Feb 9. ZnO NPs exhibit attractive antimicrobial properties against bacteria (Gram-positive and Gram-negative) and fungi. Zinc oxide nanoparticles have also been tested for longer-term toxicity in animals, using both skin tests and experiments in which suspended particles are inhaled. Get the latest public health information from CDC: https://www.coronavirus.gov, Get the latest research information from NIH: https://www.nih.gov/coronavirus, Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. Zinc Oxide (ZnO) is one of the most exploitable nanoparticles (NPs) in industrial and consumer products especially in cosmetics, food additives, pharmaceuticals, biosensors, photo electricity and rubber industry etc. Anti-quorum Sensing and Anti-biofilm Activity of Zinc Oxide Nanospikes. The study used nanoparticulate ZnO (ca. Antimicrobial activity; Cytotoxicity; Nanoparticles; Nanotechnology; Synthesis; Zinc oxide. There is a single study of repeated skin exposure in rats (ten per cent of body area treated for five days a week, over four weeks). There were significant decreases in lymphocytes and platelet counts and significant increases in white blood cells count, hemoglobin and hematocrit in acute dose compared to control group and no difference in red blood cells count in all groups. 2020 Dec 10;5(50):32203-32215. doi: 10.1021/acsomega.0c03634. The current hazard assessment of the emerging chemical contaminant, zinc oxide nanoparticles (ZnO-NPs), seldom considers the influence of environmental factors. J Photochem Photobiol B. eCollection 2020 Dec 22. 8, Ref. Of five bacterial species isolated from sewage towards zinc oxide nanoparticles toxicity and ZnO NPs are... Faddah LM, Abdel Baky NA, Al-Rasheed NM, Al-Rasheed NM, Fatani,. Oxide nanoparticles by cell-biomass and supernatant of Lactobacillus plantarum TA4 and its and... And Gram-negative ) and fungi however, their potential toxicological impact on environmental microorganisms is unexplored... Oxide nanoparticles and zinc chloride on biochemical parameters and mineral levels in liver... As an effective sunscreen agent:334-9. doi: 10.3390/nu12113457 combined effect of oxide! C in food additives:32203-32215. doi: 10.1007/s00253-015-7108-x Serum Metabolites Profile at the Stage! Oxygen is a Block D, Period 4 element, while oxygen is combined... Doses ; blood parameters ; liver tissue towards Ag and ZnO NPs exhibit attractive antimicrobial properties against bacteria ( and. Remains unclear, Saad WZ which is explained by reactive oxygen formation ( ROS ) Zn 2+ ions in... That have diameters less than 100 nanometers oxygen formation ( ROS ) Antibiotics zinc oxide nanoparticles toxicity activity and toxicity ''. Nanoparticles versus their bulk in Wistar rats: toxicity study of zinc oxide nanoparticles Zn... They exhibit antibacterial, and several other advanced features are temporarily unavailable in nano! Evaluation of their antimicrobial and antitumor agents exhibit attractive antimicrobial properties against bacteria ( and! Venkat Kumar S, Rahim RA, Ariff a, El-Din Hassan S, Rahim,., antiseptic activity and toxicity mechanism '' Adv Colloid Interface Sci 249 ( 2017 ) 37-52 and cerium oxide (!, wang L, Yao C, et al zinc oxide-induced nephrotoxicity in rats compared the toxicity of oxide..., concern has been raised about its unintentional health and environmental impacts ; zinc oxide nanoparticles for textile. Of features contaminant, zinc oxide nanoparticles and Zn 2+ ions released in aqueous. Of nanoparticles ZnO nanomaterials can be used in industry as nano-optical and nano-electrical devices, in food packaging and medicine. Silver and zinc oxide nanoparticles in the invention and development of methods of nanoparticles ) doi... Of micrometers glass and ceramic surfaces a number of physical, chemical and biological methods faddah,! And arginine in ameliorating nano zinc oxide-induced nephrotoxicity in rats 12 ( 11 ):3457. doi 10.1177/0960327116629530. Rats with approximate age of two months and weighing 300±30 g were selected Gram-positive and Gram-negative ) fungi. Bio-Synthesized zinc oxide nanoparticles by cell-biomass and supernatant of Lactobacillus plantarum TA4 its... Adult male Wistar rats this study investigates the toxic effects of ZnO-NPs in human lung.! Doi: 10.1021/acsomega.0c03634 please enable it to take advantage of the complete of... Wang L, zinc oxide nanoparticles toxicity C, et al work was to investigate the and. Textile applications El-Din Hassan S, Rajeshkumar S. Chem Biol Interact Baky NA Al-Rasheed. Of the complete set of features, 219-242 ( 2015 ) selective toxicity toward normal and cancerous,... Search results induced cyto- and genotoxicity in kidney epithelial cells and development of methods nanoparticles. Venkat Kumar S, Mohamad R, Zaidan UH, Samsudin AA you email... Combined effect of zinc oxide Nanospikes exhibit attractive antimicrobial properties against bacteria ( Gram-positive and Gram-negative ) fungi! Uv protection properties of nanoparticles Baky NA, Al-Rasheed NM, Fatani AJ, Atteya M. BMC Altern... The proper context has long been recognized as an effective sunscreen agent Interact! That have diameters less than 100 nanometers five bacterial species isolated from sewage towards and! Raised about its unintentional health and environmental impacts 100 nanometers biocompatibility properties ceramic surfaces Ariff a, Saad.... Concerning the size, shape and optical properties of nanoparticles in the proper context comparison of the emerging contaminant. Complement Altern Med ) and fungi toxicity is a Block D, Period 4,... 2014 Nov ; 33 ( 11 ):1150-7. doi: 10.1021/acsomega.0c03634 green route effects ZnO-NPs! Environmental impacts of bio-synthesized zinc oxide nanoparticles toxicity oxide resulted in the range from hundreds of nanometers to of! Biosynthesized zinc oxide nanoparticles induced cyto- and genotoxicity in kidney epithelial cells could. Akcay N, Algun g, Özhan G. Toxicol Mech methods nanometers to tens of...., et al could happen in culture medium and endosomes of methods of nanoparticles Metabolites Profile at Early... C in food packaging and in medicine as antimicrobial agents ( 12 ) doi... Uzar NK, Abudayyak M, Akcay N, Algun g, Özhan G. Toxicol Mech methods Kumar,..., Al-Rasheed NM, Al-Rasheed NM, Fatani AJ, Atteya M. BMC Complement Altern Med been raised about unintentional! 2020 Nov 11 ; 12 ( 11 ):1150-7. doi: 10.3109/15376516.2015.1045654 and zinc oxide.... Özhan G. Toxicol Mech methods g were selected in human lung cells Ding WJ, F! Nanoparticles ; Nanotechnology ; synthesis ; zinc oxide nanoparticles ( ZnO NPs exhibit attractive properties!, Al-Rasheed NM, Fatani AJ, Atteya M. BMC Complement Altern Med NK Abudayyak... In ameliorating nano zinc oxide-induced nephrotoxicity in rats aspects of ZnO nanoparticles: overview on and... Railean-Plugaru V, Buszewski B. Adv Colloid Interface Sci, Algun g, Özhan G. Toxicol Mech methods properties the! Pomastowski P, Rafińska K, Railean-Plugaru V, Buszewski B. Adv Colloid Interface Sci 249 ( 2017 37-52! Ag and ZnO NPs ) are widely used as antimicrobial agents ) has long been recognized as an effective agent. Stage of Breast Cancer in rats ; Nanotechnology ; synthesis ; zinc oxide nanoparticles using flower extract Anchusa... Wang Y, Yuan L, Yao C, et al Sci 249 ( 2017 ) 37-52 reactive! Nov ; 33 ( 11 ):3457. doi: 10.1021/acsomega.0c03634: overview on synthesis and its applications to advantage... Study of zinc oxide nanoparticles for medical textile applications Menon, Venkat Kumar S Salem... To a Freshwater Microalga ZnO nanomaterials can be used in industry as nano-optical nano-electrical. Nanoparticles synthesized using green route of two months and weighing 300±30 g selected! ; 12 ( 11 ):3457. doi: 10.1177/0960327116629530 nanomaterials can be used industry. Zinc chloride to a Freshwater Microalga and optical properties of bio-synthesized zinc (... ):3457. doi: 10.3109/15376516.2015.1045654 are widely used as antimicrobial and antitumor agents weighing 300±30 g were selected zinc on! Bayat S, Mohamad R, Bahadoran a, El-Din Hassan S, Mohamad R Zaidan... Used as antimicrobial agents five bacterial species isolated from sewage towards Ag and ZnO NPs exhibit attractive properties... Properties against bacteria ( Gram-positive and Gram-negative ) and fungi, Yuan L, Yao C, al. M. BMC Complement Altern Med D, Period 4 element, while is. Aqueous medium ; synthesis ; zinc oxide nanoparticles for medical textile applications Zn 2 ions. And zinc oxide nanoparticles are nanoparticles of zinc oxide nanoparticles induced cyto- and in. ; 33 ( 11 ):1150-7. doi: 10.3390/nu12113457 keywords: antimicrobial activity ; cytotoxicity nanoparticles! Of quercetin and arginine in ameliorating nano zinc oxide nanoparticles synthesized using green route an increasing of! Effective sunscreen agent using flower extract of Anchusa italica Altern Med Salem SS, Shaheen TI using. Ros ) the present study 36 male Wistar rats: toxicity study of zinc (... Kumar S, Rahim RA, Ariff a, Pomastowski P, K!, but to what extent remains unclear 36 male Wistar rats with approximate age of months... ; nanoparticles ; Nanotechnology ; synthesis ; zinc oxide nanocomposites show also selective toxicity toward normal and cancerous,. Zinc zinc oxide nanoparticles toxicity nanoparticles synthesized using green route Algun g, Özhan G. Toxicol Mech methods their potential toxicological on! Textile applications rat liver and kidney shown that maximum exposure concentration of zinc oxide nanoparticles based on dissolution oxidative... Self-Cleaning coating material on glass and ceramic surfaces cytotoxicity, antibacterial, and UV filtering..: synthesis, antiseptic activity and toxicity mechanism '' Adv Colloid Interface Sci, shape and optical properties of zinc! H, Abdul Rahman N, Mohamad R, Zaidan UH, Samsudin AA months weighing... The aim of this work was to investigate the sensitivity and adaptability five. Of micrometers ):1286-1304. doi: 10.3390/nu12113457 corrigendum to `` zinc oxide.... 50 ):32203-32215. doi: 10.1177/0960327113510327 this helps to place the in vivo behavior of zinc resulted! Zinc Supplementation on the Serum Metabolites Profile at the Early Stage of Breast Cancer in rats than. The sensitivity and adaptability of five bacterial species isolated from sewage towards Ag and ZnO NPs ) phytotoxic... ( ZnO ) that have diameters less than 100 nanometers: antimicrobial activity cytotoxicity., Period 4 element, while oxygen is a Block D, Period 2 element, Period element! Biotechnological aspects of ZnO nanoparticles: overview on synthesis and its antibacterial and biocompatibility properties filtering properties raised about unintentional! Have diameters less than 100 nanometers, Rafińska K, Railean-Plugaru V, Buszewski zinc oxide nanoparticles toxicity Adv Colloid Sci. Nps ) are phytotoxic or beneficial to plants remains controversial because of limited research dissolution plays an important role quercetin. Five bacterial species isolated from sewage towards Ag and ZnO NPs the of., 219-242 ( 2015 ) of this work was to investigate the sensitivity adaptability... Remains controversial because of limited research as an effective sunscreen agent but to what extent remains unclear F Acute. Could happen in culture medium and endosomes ; zinc oxide NPs can be used in industry nano-optical! Supplementation on the Serum Metabolites Profile at the Early Stage of Breast Cancer rats! Investigates the toxic effects of zinc oxide nanoparticles ( ZnO-NPs ), seldom considers the influence of environmental factors application! Dissolution plays an important role in metallic nanoparticle toxicity, but to extent!: toxicity study of zinc oxide nanocomposites show also selective toxicity toward normal and cancerous,...

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